Regulatory perspectives also differ across countries. In South Korea and Singapore, the injections are permitted under medical supervision, while in the United States, the Food and Drug Administration has approved only topical formulations of salmon-derived serums. Nevertheless, some clinics in the U.S. discreetly offer injections, while others incorporate the serum into microneedling procedures as a workaround. This regulatory gray area has sparked debates within the medical community about safety, oversight, and the ethics of promoting experimental treatments.
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